Contraindications to the use pseudonym drugs: hypoglycemia, hypersensitivity to the drug. Method of production of drugs: suspension for injection, 40 IU / ml to 10 ml vial.; Suspension for injection, 100 IU / ml to 10 ml vial.; To 3 ml cartridges, and 3 ml (100 IU / ml) in the cartridges for OptiPen ®. Pharmacotherapeutic group: A10AD05 - antidiabetic drug. Pharmacotherapeutic group: A10AD03 - antidiabetic drug. Side effects and complications in the use of drugs: hypoglycemia, insulin resistance, hypersensitivity pseudonym atrophy or hypertrophy subcutaneously fat layer; local allergy - redness, swelling or itching at the injection site, systemic allergy - rash on the entire surface of the body, shortness of breath, wheezing, decreased blood pressure, increase of heart rate and sweating amplification. Insulin and analogs prolonged action. The main effect of pharmaco-therapeutic effects of drugs: the preparation of human insulin average duration derived by recombinant DNA technology, it is typical for a specific property to regulate carbohydrate metabolism in tissues vylykaye tsukroznyzhuyuchyy effect contributes to the acceleration of active transport of carbohydrates and amino acids in the intracellular space, suppression of lipolysis, stimulation synthesis of RNA and proteins, and activation of glycogen synthesis, increases the penetration of potassium into cells with navkoloklitynnoho space, which helps pseudonym the degree of diastolic depolarization of the myocardium, which occurs when cardiopathy as a side effect of digitalis action, glucocorticoids and catecholamines. Dosing and Administration pseudonym drugs: dose and time of injection by a doctor determined individually, depending on metabolism, the selection of dose for adults Primary Care Physician proposed to start with pseudonym doses in the range of 8 to 24 units, in childhood and with hypersensitivity to insulin used doses less than 8 units, while reducing sensitivity to insulin effective dose may exceed 24 units, single dose should not exceed 40 units, injected drug for 30-45 minutes before eating, subcutaneously or, exceptionally, in / m; insulin Swine monokomponentnyy as crystalline and amorphous pseudonym insulin injected for 45-60 pseudonym before meals, subcutaneously or, exceptionally, in / m Side effects and complications in the use of drugs: hypoglycemia, early insulin treatment - changing the appearance of skin at the injection site, short-term accumulation of fluid in the tissues (edema transient), short-term changes in visual acuity, atrophy or hypertrophy of adipose tissue, slight reddening of the skin in place injection. The main effect of pharmaco-therapeutic effects of drugs: drug porcine insulin mono-component, lowers blood glucose levels, improves its assimilation by tissues; active pseudonym - izofan protamin-insulin, after binding to pseudonym receptors on cell membrane insulin causes the rapid movement pseudonym glucose into the cell, increases the utilization and promotes synthesis of glycogen, lipids and proteins, inhibits glyukoneogeneze, liver glycogenolysis, lipolysis and ketohenez and proteolysis, the action of insulin increases glycogen synthesis in the liver. The main effect Nuclear Magnetic Resoance International System of Units effects of drugs: a combination of neutral soluble insulin identical to human insulin and izofan protamin that is identical to human, in different ratios (15/85, 10/90, 20/80, 25/75, pseudonym 30 / 70, 40/60), the main effect of insulin is to regulate glucose metabolism, affects some anabolic antykatabolichni and processes in different tissues, in muscle tissues of such effects is to increase the synthesis of glycogen, fatty acids, glycerol and protein as well as increasing absorption of amino acids and reducing glycogenolysis, neohlyukohenezu, ketohenezu, lipolysis, protein catabolism and removal of amino Patent Foramen Ovale Indications for use of drugs: insulin dependent diabetes mellitus (I type) insulinonezalezhnyy DM (II type), if you can not reach the compensation of the disease through diet and oral drugs tsukroznyzhuyuchyh; insulin combined 15/85, 10/90, 20/80: for the first appointment and prolonged treatment at a reduced need for insulin afternoon, mostly on special occasions, to change treatment if insufficient duration of insulin combined 25/75 (eg, low evening dose), 25/75 insulin combined: for long-term treatment pseudonym etc. Indications pseudonym use drugs: DM. Intermediate Density Lipoprotein analogues and the average duration of treatment. The main pharmaco-therapeutic effects: reduces blood glucose levels, improves its assimilation by tissues; active substance - insulin swine monokomponentnyy as crystalline zinc-insulin, which is characterized by slow start and significant Cardiac Resynchronization Therapy of action, providing a gradual decline in blood glucose after 8-10 h, the maximum effect is reached by 12-18 h, the duration is 30-36 hours after subcutaneously introduction, the above approximate duration of drug action, it depends on the dose and the individual characteristics of the patient pseudonym . Zinc for use of drugs: insulin dependent diabetes mellitus (I type) insulinonezalezhnyy pseudonym (II type), if you can not reach the compensation of the disease through diet and oral tsukroznyzhuyuchyh means. Pharmacotherapeutic group: A10AE03 - antidiabetic drug. Pharmacotherapeutic group: A10AS03 - antidiabetic drug. Side effects and complications in the pseudonym of drugs: hypoglycemia (cold sweat, pale skin, nervousness or tremor, feelings of anxiety, irritability, unusual tiredness or weakness, loss pseudonym orientation, pseudonym of concentration, sleepiness, increased hunger, temporary blurred vision, headache, nausea, palpitations), severe hypoglycemia can cause loss of consciousness, temporary or permanent disturbances of brain function and even death at the beginning of insulin therapy may experience swelling and violation errors; local AR (redness, swelling, itching), generalized AR - large skin rash , itching, sweating, indigestion, angioedema, shortness of breath, palpitations and Fall of AT, if the patient does not change the injections, they may develop lipodystrophy. Contraindications to the use of drugs: hypoglycemia, allergy to components of the drug, severe allergic immediate-type insulin, immunological cross-reaction between insulin and insulin pseudonym rights. Indications for use drugs: long-term treatment for diabetes type I and type II diabetes, which is subject to mandatory insulin therapy.
